HomeMarket News European Medicines Agency Investigates GLP-1s and Suicidal Thoughts Amidst...

European Medicines Agency Investigates GLP-1s and Suicidal Thoughts Amidst Growing Concerns

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European regulators are intensifying their focus on the possible link between certain diabetes and weight-loss drugs, known as GLP-1s, and suicidal thoughts. The European Medicines Agency (EMA) has launched an investigation in response to numerous reports of adverse events possibly associated with these medications, involving key players in the industry such as Novo Nordisk (NVO) and Eli Lilly (NYSE:LLY).

The EMA initiated the review in July following the receipt of over 170 reports detailing suspected adverse events related to the drugs in question. This week, the EMAโ€™s Pharmacovigilance Risk Assessment Committee convened to deliberate the matter and plans to reconvene on the issue in April, as per a report from Reuters.

According to Reuters, the EMA has emphasized, โ€œWhile at this point no conclusion can be drawn on causal association, there are several issues that still need to be clarified.โ€

Notably, the review is centered on GLP-1 receptor agonists, a category of medications encompassing Novo Nordiskโ€™s Rybelsus, Saxenda, Wegovy, and Ozempic; Lillyโ€™s Trulicity; AstraZenecaโ€™s (NASDAQ:AZN) Bydureon and Byetta; as well as Sanofiโ€™s (NASDAQ:SNY) Suliqua. However, it excludes Lillyโ€™s Mounjaro and Zepound, which belong to a different molecular class.

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