HomeMost PopularInvestingLights, Camera, Action! Exelixis (EXEL) Shines Bright, Gains 30% YTD on Cabometyx...

Lights, Camera, Action! Exelixis (EXEL) Shines Bright, Gains 30% YTD on Cabometyx Success

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A Beacon in the Industry

Amidst the tumultuous waves of the biotech industry, Exelixis, Inc. continues to stand tall as a beacon of success. With a staggering 30.9% surge in its shares year to date, the company has outshone the industry’s decline of 22.5%, making it a standout performer in 2023.

Zacks Investment Research
Image Source: Zacks Investment Research

Rocky Third-Quarter Results

This oncology-focused drug company faced turbulence in its recent third-quarter results, with earnings and sales missing estimates due to increased R&D expenses putting pressure on the bottom line. However, amidst the storm, Cabometyx emerged as a resilient force, maintaining its position as the leading tyrosine kinase inhibitor (TKI) for the treatment of renal cell carcinoma (RCC). Its collaboration with Bristol Myers’ Opdivo in the first-line setting continued to drive its success, showing robust growth in the hepatocellular carcinoma.

Cabometyx prescription volume showcased an 8% year-over-year increase, reflecting strong demand and new patient starts, solidifying the drug’s market stronghold.

Bright Pipeline and Strategic Moves

Exelixis marked significant progress in its pipeline, aiming to expand Cabometyx’s label and diversify its portfolio with promising candidates like zanzalintnib, XB002, XL102, and CBX-12. The company’s exclusive license agreement with Insilico Medicine to develop ISM3091 further solidifies its strategic moves.

Explosive Potential

The company recently announced positive results from the expansion cohort of STELLAR-001, demonstrating the potential of zanzalintinib in treating previously clear cell renal cell carcinoma, as well as its promise in advanced solid tumors. Moreover, the successful data from the late-stage CONTACT-02 study for the treatment of metastatic castration-resistant prostate cancer (mCRPC) has opened new avenues of hope.

Setbacks Turned Triumphs

The recent settlement of patent litigation with Teva Pharmaceuticals, allowing Exelixis to retain market exclusivity for Cabometyx until Jan 1, 2031, emerged as a major win, offering a clear path for future growth. Additionally, the share repurchase program of $550 million reflects the company’s commitment to enhancing shareholder value.

Road Ahead

Despite the challenges posed by a competitive market, Exelixis remains steadfast in its pursuit. The successful development of additional drugs will broaden its portfolio and reduce its dependency on Cabometyx, affirming its potential for sustained growth.

Parting Words

As we witness the bright glow of Exelixis in an otherwise dark industry landscape, the company’s commitment to innovation and growth sends ripples of optimism. With each success, Exelixis charts a compelling narrative of resilience, a narrative destined to captivate the stage for years to come in the biotech industry!

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

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