January 4, 2024
Investors Cheer Positive Results in Atai Life Sciences MDMA Study
Atai Life Sciences Shows Positive Results In Phase 1 Clinical Study For PTSD Treatment
Biopharma firm Atai Life Sciences ATAI has announced the positive outcomes of a Phase 1 clinical study on MDMA R-enantiomer, EMP-01, developed for the potential treatment of PTSD. Assessing EMP-01’s safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD,) the study enrolled 32 healthy participants. They were divided into four cohorts that received one dose of 75mg, 125mg, 175mg, or 225mg of EMP-01 or placebo in a 6+2 design. Atai reported that: The compound was well-tolerated, and treatment-related adverse events were all expected, none severe and generally dose-dependent. Non-clinically significant increases in blood pressure and heart rate were observed, yet changes showed limited dose dependency.